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Phospho-mTOR (Ser2481) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA538374
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Descripción
Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation.
Especificaciones
| Phospho-mTOR (Ser2481) | |
| Polyclonal | |
| Unconjugated | |
| MTOR | |
| mTOR, MTOR, m-TOR, Mechanistic Target Of Rapamycin, Mammalian Target Of Rapamycin, FRAP, FRAP1, FRAP2, FK506 binding protein 12-rapamycin associated protein, FKBP-Rapamycin Associated Protein, Rapamycin Target Protein, Serine/Threonine-Protein Kinase MTOR, EC 2.7.11.1, RAFT1, RAPT1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 2475, 56717, 56718 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P42345, Q9JLN9, P42346 | |
| MTOR | |
| A synthetic phosphopeptide derived from human mTOR around the phosphorylation site of Ser2481 (I-H-SP-F-I) | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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