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Invitrogen™ Phospho-MKP3 (Ser197) Polyclonal Antibody
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Código de producto. 16622455
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Cantidad:
100 μL
Unit Size:
100 microlitros
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16622455 100 μL 100 microlitros
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Product Code. 16622455 Supplier Invitrogen™ Supplier No. PA5106011

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of DUSP6 only when phosphorylated at Ser197.

DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Twotranscript variants encoding different isoforms have been found for the DUSP6 gene.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno Phospho-MKP3 (Ser197)
Aplicaciones Immunohistochemistry (Paraffin), Western Blot
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
génica DUSP6
N.º de referencia del gen Q16828, Q64346, Q9DBB1
Alias de gen 1300019I03Rik; dual specificity phosphatase 6; dual specificity protein phosphatase 6; Dual specificity protein phosphatase PYST1; Dusp6; DUSP6-ALT; HH19; MAP kinase phosphatase 3; mitogen-activated protein kinase phosphatase 3; Mkp3; MKP-3; PYST1; serine/threonine specific protein phosphatase
Símbolos de los genes DUSP6
Especie del huésped Rabbit
Inmunógeno A synthesized peptide derived from human DUSP6(Accession Q16828), corresponding to amino acid residues around phosphorylated Ser197.
Método de purificación Sequential Chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 116663, 1848, 67603
Especies diana Human, Mouse, Rat
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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