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Invitrogen™ Phospho-JNK1/JNK2 (Thr183, Tyr185) Polyclonal Antibody
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Código de producto. 11518691
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Cantidad:
30 μL
Tamaño de la unidad:
30 microlitros
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11518691 30 μL 30 microlitros
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Código de producto. 11518691 Proveedor Invitrogen™ N.º de proveedor PA19593

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Rabbit Polyclonal Antibody

PA1-9593 detects Phospho-JNK/SAPK in human, mouse, and rat samples. PA1-9593 has been successfully used in Western blot, immunohistochemistry, and immunocytochemistry procedures. By Western blot, PA1-9593 detects a 46 kDa and 54 kDa protein representing Phospho-JNK/SAPK. PA1-9593 immunogen is a phosphorylated peptide (pT183-P-pY185) based on human JNK.

C-Jun N-terminal Kinase (JNK) is also known as Mitogen-activated protein kinase (MAPK8). It belongs to the MAPK superfamily of stress-activated protein kinases. MAPKs are Serine-threonine protein kinases that are activated in response to a variety of extracellular stimuli, and mediate signal transduction from the cell surface to the nucleus. JNK is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK pathways are activated by stress and inflammatory signals. JNK is expressed as ten different isoforms due to differential mRNA splicing. The predominant forms are JNK1 and JNK2.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Phospho-JNK1/JNK2 (Thr183, Tyr185)
Aplicaciones Immunohistochemistry, Western Blot, Immunocytochemistry
Clasificación Polyclonal
Concentración 0.5 mg/mL
Conjugado Unconjugated
Formulación PBS with no preservative
génica MAPK8
N.º de referencia del gen P45983, P45984, P49185, P49186, Q91Y86, Q9WTU6
Alias de gen AI849689; AI851083; C-jun kinase; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; I79_012561; JNK; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; JNK2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 8; MAP kinase 9; MAPK; MAPK 8; MAPK 9; Mapk8; Mapk9; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; OTTHUMP00000019552; p54 gamma; p54a; p54-alpha; p54aSAPK; Phospho-JNK; PRKM; PRKM8; Prkm9; protein kinase JNK1; protein kinase mitogen-activated 8; protein kinase, mitogen-activated 9; SAPK; SAPK 1; SAPK gamma; SAPK1; SAPK1A; SAPK1c; SAPK-alpha; stress activated protein kinase alpha II; stress-activated protein kinase 1; stress-activated protein kinase 1a; Stress-activated protein kinase 1c; stress-activated protein kinase JNK1; Stress-activated protein kinase JNK2
Símbolos de los genes MAPK8, MAPK9
Especie del huésped Rabbit
Inmunógeno Phosphorylated peptide (pT183-P-pY185) based on human JNK.
Método de purificación Affinity chromatography
Cantidad 30 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 116554, 26419, 26420, 50658, 5599, 5601
Especies diana Human, Mouse, Rat
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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