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Invitrogen™ Phospho-c-Met (Tyr1234, Tyr1235) Monoclonal Antibody (G.941.2)
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Código de producto. 11545051
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
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11545051 100 μL 100 microlitros
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Código de producto. 11545051 Proveedor Invitrogen™ N.º de proveedor MA515083

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Descripción

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

MET (cMET) is a receptor-like tyrosine kinase whose dysregulation has been linked to many types of human malignancies. After activation of the ligand, MET interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, and STAT3. There interactions lead to the activation of signaling cascades including RAS-ERK, PI3, kinase-AKT, and PLCgamma-PKC. MET plays a role in embryonic development including gastrulation, development of muscles and neurons, angiogenesis, and kidney formation. It also plays a role in adults including wound healing, organ regeneration, and tissue remodeling. MET has been linked to cancers including gastric, renal, and breast; therefore, making it a target for cancer therapeutics and diagnostic testing.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Phospho-c-Met (Tyr1234, Tyr1235)
Aplicaciones Western Blot
Clasificación Monoclonal
Clon G.941.2
Concentración 118 μg/mL
Conjugado Unconjugated
Formulación 0.01M HEPES with 100 μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
génica MET
N.º de referencia del gen P08581, P16056, P97523
Alias de gen AI838057; AUTS9; bHLHe59; CG1705; CG1705-PA; CG1705-PB; cmet; c-met; c-met proto-oncogene; c-Met receptor tyrosine kinase; c-Met/HGF receptor; D249; DFNB97; Dmel\CG1705; Dmel_CG1705; DmMet; EC 2.7.10.1; Hepatocyte growth factor receptor; HGF; HGF receptor; HGF receptor c-Met; HGF/SF receptor; HGFR; HGF-SF receptor; juvenile hormone resistance; met; met proto-oncogene; met proto-oncogene (hepatocyte growth factor receptor); met proto-oncogene tyrosine kinase; MET proto-oncogene, receptor tyrosine kinase; Met/Met1; Met; protein tyrosin kinase; methoprene tolerant; Methoprene-tolerant; Methoprene-tolerant protein; Met-PA; Met-PB; Mett; oncogene MET; Par4; Proto-oncogene c-Met; RCCP2; resistance (1) juvenile H; resistance to juvenile hormone; Rst(1)JH; sc MET; scatter factor receptor; SF receptor; soluble c met; tyrosine-protein kinase Met
Símbolos de los genes MET
Especie del huésped Rabbit
Inmunógeno Synthetic phosphopeptide corresponding to residues surrounding pTyr1234/1235 of human Met.
Método de purificación Affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 17295, 24553, 4233
Especies diana Human, Mouse, Rat
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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