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  6. Invitrogen™ Phospho-c-Cbl (Tyr700) Recombinant Rabbit Monoclonal Antibody (CblY700-E1), Invitrogen™

Invitrogen™ Phospho-c-Cbl (Tyr700) Recombinant Rabbit Monoclonal Antibody (CblY700-E1), Invitrogen™

Código de producto. 17176938 Tienda Thermo Scientific Productos
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Cantidad:
20 μL
200 μL
Tamaño de la unidad:
20 microlitros
200 microlitros
Código de producto. Cantidad unitSize
17176938 20 μL 20 microlitros
17116698 200 μL 200 microlitros
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Codice prodotto. 17176938

Marca: Invitrogen™ MA537351

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Descrizione

Rabbit Recombinant Monoclonal Antibody

Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.
TRUSTED_SUSTAINABILITY

Specifica

Antígeno Phospho-c-Cbl (Tyr700)
Aplicaciones Flow Cytometry
Clasificación Recombinant Monoclonal
Clon CblY700-E1
Concentración 0.5 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.10% BSA, 50% glycerol and 0.02% sodium azide
génica Cbl
N.º de referencia del gen P22681, P22682
Alias de gen 4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL
Símbolos de los genes Cbl
Especie del huésped Rabbit
Inmunógeno A synthetic phospho-peptide corresponding to residues surrounding Tyr700 of human phospho c-Cbl.
Método de purificación Protein A/G
Cantidad 20 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 12402, 500985, 867
Especies diana Human, Mouse, Rat
Contenido y almacenamiento -20°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG κ
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Titolo del prodotto
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