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  6. Invitrogen™ Phospho-Ask1 (Ser83) Recombinant Rabbit Monoclonal Antibody (Ask1S83-G4), PE, Invitrogen™

Invitrogen™ Phospho-Ask1 (Ser83) Recombinant Rabbit Monoclonal Antibody (Ask1S83-G4), PE, Invitrogen™
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Código de producto. 17106568 Tienda Thermo Scientific Productos
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100 Tests
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Código de producto. Cantidad unitSize
17106568 100 Tests paquete de 100
17176848 10 Tests paquete de 10
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Código de producto. 17106568

Marca: Invitrogen™ MA536974

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Description

Rabbit Recombinant Monoclonal Antibody

MAP3K5 (ASK1) is a serine/threonine kinase that is abundantly expressed in human heart and pancreas and are activated in response to various extracellular stimuli, including cytokines, growth factors and environmental stresses. A novel MAP kinase kinase kinase (MAPKKK) was identified and designated ASK1 (for apoptosis signal-regulating kinase 1) and MAPKKK5. ASK1 activates two different subgroups of MAPKK, MKK4 and MKK6, which in turn activates c-Jun N-terminal kinase (JNK) and p38 MAP kinase, respectively. ASK1/MAPKKK5 is activated by TNFR and Fas through the interaction with members of the TRAF family and Fas-associated protein Daxx. Overexpression of ASK1 induced apoptotic cell death and a catalytically inactive form of ASK1 inhibited TNF-a-induced apoptosis. ASK1 is expressed in variety of human and mouse tissues.
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Specifications

Antígeno Phospho-Ask1 (Ser83)
Aplicaciones Flow Cytometry
Clasificación Recombinant Monoclonal
Clon Ask1S83-G4
Conjugado PE
Formulación PBS with 0.20% BSA and 0.09% sodium azide
génica MAP3K5
N.º de referencia del gen O35099, Q99683
Alias de gen 7420452D20Rik; apoptosis signal regulating kinase 1; apoptosis signal-regulating kinase 1; ASK; ASK 1; ASK1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP/ERK kinase kinase 5; Map3k5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; Mekk5; mitogen activated protein kinase kinase kinase 5; mitogen-activated protein kinase kinase kinase 5; RGD1306565; RP3-325F22.4
Símbolos de los genes MAP3K5
Especie del huésped Rabbit
Inmunógeno A synthetic phospho-peptide corresponding to residues surrounding Ser83 of human phospho Ask1.
Método de purificación Protein A/G
Cantidad 100 Tests
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 26408, 365057, 4217
Especies diana Human, Mouse, Rat
Contenido y almacenamiento 4°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG κ
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