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Invitrogen™ PGAM5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA557894
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Descripción
Immunogen sequence: NWDRREPLSL INVRKRNVES GEEELASKLD HYKAKATRHI FLIRHSQYHV DGSLEKDRTL TPLGREQAEL TGLRLASLGL KFNKIV Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.
Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore. [UniProt].
Especificaciones
| PGAM5 | |
| Polyclonal | |
| Unconjugated | |
| PGAM5 | |
| 2610528A17Rik; Bcl-XL-binding protein v68; BXLBV68; PGAM family member 5, mitochondrial serine/threonine protein phosphatase; PGAM family member 5, serine/threonine protein phosphatase, mitochondrial; PGAM5; Phosphoglycerate mutase family member 5; RGD1312028; serine/threonine-protein phosphatase PGAM5, mitochondrial | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 192111 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q96HS1 | |
| PGAM5 | |
| Recombinant protein corresponding to Human PGAM5. Recombinant protein control fragment (Product #RP-95712). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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