missing translation for 'onlineSavingsMsg'
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Description
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function.
Specifications
Specifications
| Antígeno | PERK/EIF2AK3 |
| Aplicaciones | Immunocytochemistry, Immunofluorescence, Western Blot, Immunohistochemistry (Paraffin) |
| Clasificación | Polyclonal |
| Concentración | 0.33 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| génica | EIF2AK3 |
| N.º de referencia del gen | Q9NZJ5 |
| Alias de gen | EIF2AK3, HRI, HsPEK, Pancreatic eIF2 alpha kinase, PEK, PERK, WRS |
| Símbolos de los genes | EIF2AK3 |
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Product Title
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