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Invitrogen™ Pellino 2 Polyclonal Antibody

Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA562754
Descripción
Immunogen sequence: NRKEVVEEKQ PWAYLSCGHV HGYHN Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 96%.
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1. [UniProt].
Especificaciones
| Pellino 2 | |
| Polyclonal | |
| Unconjugated | |
| Peli2 | |
| AW047589; BB129927; E3 ubiquitin-protein ligase pellino homolog 2; Peli2; pellino 2; pellino E3 ubiquitin protein ligase family member 2; pellino homolog 2; pellino-2; protein pellino homolog 2; RGD1565884; RING-type E3 ubiquitin transferase pellino homolog 2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 57161 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9HAT8 | |
| Peli2 | |
| Recombinant protein corresponding to Human Pellino 2. Recombinant protein control fragment (Product #RP-100026). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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