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Invitrogen™ PDE6D Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA522008
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Descripción
Recommended positive controls: Molt-4, mouse eye. Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (90%), Dog (98%), Rhesus Monkey (99%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PrBP/delta, previously known as PDE6/delta, is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system. There are five different subunits consisting of rod and cone specific catalytic subunits: alpha (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family). PRBP/delta has been implicated in the transport and membrane targeting of prenylated proteins (including PDE6) from their site of synthesis in the inner segment to their final destination in the outer segment of rods and cones (Norton et. al., 2005).
Especificaciones
| PDE6D | |
| Polyclonal | |
| Unconjugated | |
| PDE6D | |
| AI841218; GMP-PDE delta; JBTS22; PDE6D; PDED; phosphodiesterase 6D; phosphodiesterase 6D, cGMP-specific, rod, delta; PrBP/delta; Protein p17; retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; rod phosphodiesterase delta subunit | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 18582, 5147 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 0.17 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
| O43924, O55057 | |
| PDE6D | |
| Full length human PDE6D Recombinant protein. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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