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Invitrogen™ PDE4B Polyclonal Antibody

Descripción
This antibody is predicted to react with human and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Especificaciones
Especificaciones
| Antígeno | PDE4B |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Polyclonal |
| Concentración | 0.5 mg/mL |
| Conjugado | Unconjugated |
| Formulación | TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 |
| génica | PDE4B |
| N.º de referencia del gen | Q07343 |
| Alias de gen | 3',5'-cyclic AMP phosphodiesterase; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; DKFZp686F2182; DPDE4; dunce; dunce-like phosphodiesterase E4; MGC126529; MGC93193; OTTHUMP00000046896; PDE32; PDE4/IVb; PDE4B; Pde4B1; Pde4B2; Pde4B3; Pde4B4; PDEIVB; phosphodiesterase 4B; Phosphodiesterase 4B cAMP-specific (dunce; phosphodiesterase 4B, cAMP specific; phosphodiesterase 4B, cAMP-specific; Phosphodiesterase 4B, cAMP-specific (dunce; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila); R74983; RP5-876C12.1 |
| Símbolos de los genes | PDE4B |
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Título del producto
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