missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ PD-L1 Polyclonal Antibody
Goat Polyclonal Antibody
Marca: Invitrogen™ PA518337
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
Especificaciones
| PD-L1 | |
| Polyclonal | |
| Unconjugated | |
| Cd274 | |
| A530045L16Rik; B7 homolog 1; B7-H; B7h1; B7-H1; Cd274; CD274 antigen; CD274 molecule; PDCD1 ligand 1; Pdcd1l1; Pdcd1lg1; Pdl1; PD-L1; pdl-1; Programmed cell death 1 ligand 1; programmed death ligand 1; RGD1566211; sCD274; soluble CD274; soluble PD L1; sPD L1 | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 29126 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q9NZQ7 | |
| Cd274 | |
| Synthetic peptide sequence (CKKQSDTHLEET) corresponding to the C-terminus amino acids of CD274 (aa 281-290). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido