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PD-L1/CD274 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 17952-1-AP-20UL
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Descripción
PD-L1 (Programmed death receptor ligand 1, B7-H1, CD274) is a 40 kDa transmembrane protein and B7 family member. PD-L1 has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production, and PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion. Together with B7.1, PD-L1 can inactivate T cells and this relationship is a focal point of cancer therapeutic treatment. At least two isoforms of PDL-1 are known to exist.Especificaciones
| PD-L1/CD274 | |
| Polyclonal | |
| Unconjugated | |
| CD274 | |
| PD-L1/CD274 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 29126, 499342, 60533 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Flow Cytometry, Immunoprecipitation, Immunocytochemistry, Immunohistochemistry (Paraffin) | |
| 0.33 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q9EP73, Q9NZQ7 | |
| CD274 | |
| PD-L1/CD274 Fusion Protein Ag12432 | |
| 20 μL | |
| Primary | |
| Human, Rat, Mouse | |
| Antibody | |
| IgG |
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Título del producto
PD-L1/CD274 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech > 20 μL; Unconjugated
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