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Invitrogen™ PD-1 (CD279) Biosimilar Recombinant Monoclonal Antibody

Recombinant Monoclonal Antibody

477.00€ - 1204.00€

Especificaciones

Antígeno PD-1 (CD279) Humanized Biosimilar
Concentración 1 mg/mL
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Aplicaciones ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance
Clasificación Recombinant Monoclonal
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
30283539
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Invitrogen™
MA559735
100 μg
477.00€
100 microgramos
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30283788
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Invitrogen™
MA559736
1 mg
1204.00€
1 miligramo
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Description

Description

For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °. This antibody can also be cross referenced by the term UCB patent anti-PD-1.

Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of 'danger signals' such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.
Specifications

Specifications

PD-1 (CD279) Humanized Biosimilar
-20°C, Avoid Freeze/Thaw Cycles
Recombinant Monoclonal
Lyophilized
IgG4SP
Human
Primary
Protein A
1 mg/mL
ELISA, Flow Cytometry, Functional Assay, Surface Plasmon Resonance
Unconjugated
Human
RUO
25 mM histidine with 8% sucrose, 0.01% Tween 80 and no preservative; pH 6.2
Antibody
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