missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Descripción
PCP-4 (Purkinje cell protein 4), also known as PCP4, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer′s disease and Huntington′s disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.
Especificaciones
Especificaciones
| Antígeno | PCP4 |
| Aplicaciones | Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot |
| Clasificación | Polyclonal |
| Concentración | 0.22 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| génica | PCP4 |
| N.º de referencia del gen | P48539, P63054, P63055 |
| Alias de gen | Brain specific antigen PCP 4, PCP4, PEP 19, PEP19, Purkinje cell protein 4 |
| Símbolos de los genes | PCP4 |
| Mostrar más |
Título del producto
Al hacer clic en Enviar, acepta que Fisher Scientific se ponga en contacto con usted en relación con los comentarios que ha proporcionado en este formulario. No compartiremos su información para ningún otro fin. Toda la información de contacto proporcionada se mantendrá de acuerdo con nuestra Política de Privacidad. Política de privacidad.
¿Detecta una oportunidad de mejora?