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PCP4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marca: Proteintech 14705-1-AP-150UL
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Descripción
PCP-4 (Purkinje cell protein 4), also known as PCP4, is a calmodulin (CaM) regulatory protein that is highly expressed in neuronal cells. Through its IQ motif, PCP-4 mediates both the calcium-dependent binding properties of CaM and the rates of association and dissociation of calcium from the C-terminal domain of CaM. The IQ motif contains a serine residue which can be phosphorylated by all isoforms of protein kinase C (PKC). PCP-4 is implicated in uterine leiomyomas, as well as in neurodegenerative disorders such as Alzheimer′s disease and Huntington′s disease. Additionally, overexpression of PCP-4 is thought to play a role in cerebellar hypoplasia, a key feature of Down syndrome.Especificaciones
| PCP4 | |
| Polyclonal | |
| Unconjugated | |
| PCP4 | |
| Brain specific antigen PCP 4, PCP4, PEP 19, PEP19, Purkinje cell protein 4 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 18546, 25510, 5121 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.22 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P48539, P63054, P63055 | |
| PCP4 | |
| PCP4 Fusion Protein Ag6388 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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