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DiscoverX PathHunter™ eXpress ACVR1C/ACVR2B Dimerization Assay

Código de producto. 17394299
Encompass
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Cantidad:
200 dp (2 x 96-pocillos)
Tamaño de la unidad:
1 set
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Código de producto. 17394299

Marca: DiscoverX 931047E3CP5M

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Descripción

The PathHunter™ eXpress ACVR1C/ACVR2B Dimerization Assay measures ligand-induced dimerization of ACVR1C/ACVR2B . eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ ACVR1C/ACVR2B Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. activin B) induced dimerization of ACVR1C/ACVR2B receptors. This product uses EFC technology. The cell line included overexpresses ACVR2B target protein fused to PK alongside ACVR1C target protein fused to EA. Upon ligand-induced dimerization of ACVR1C/ACVR2B , detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifications

Entrada del ensayo ACVR1C/ACVR2B Dimerization
Para utilizar con (aplicación) Assay-Ready eXpress Kits
Agonista primario Activin B
Cantidad 200 dp (2 x 96-pocillos)
Entrada diana ACVR1C/ACVR2B
Línea de células U2OS
Objetivo ACVR1C/ACVR2B
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