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Invitrogen™ PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Marca: Invitrogen™ MA537358
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Descripción
Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyse the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Adp216 and Gly217, a site in PARP conserved across species.
Especificaciones
| PARP1 (cleaved Asp214) | |
| Recombinant Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.2% BSA, 50% glycerol and 0.02% sodium azide | |
| P09874 | |
| PARP1 | |
| A synthetic peptide corresponding to residues surrounding Asp214 of human PARP. | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
| Flow Cytometry, Western Blot | |
| PARP-H8 | |
| Unconjugated | |
| PARP1 | |
| 5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; Adprt; ADPRT 1; ADPRT1; AI893648; ARTD1; C80510; DNA ADP-ribosyltransferase PARP1; msPARP; NAD(+) ADP-ribosyltransferase 1; pADPRT-1; PARP; Parp1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); poly [ADP-ribose] polymerase 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein poly-ADP-ribosyltransferase PARP1; sPARP-1; synthetase fragment (AA 67); Unknown (protein for IMAGE:8023736); unnamed protein product | |
| Rabbit | |
| Protein A/G | |
| RUO | |
| 142 | |
| -20°C | |
| Liquid |
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