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Invitrogen™ PADI4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA522317
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Descripción
Recommended positive controls: PAD4-transfected 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Catalyzes the citrullination/deimination of arginine residues of proteins. Citrullinates histone H3 at 'Arg-8' and/or 'Arg-17' and histone H4 at 'Arg-3', which prevents their methylation by CARM1 and HRMT1L2/PRMT1 and represses transcription. Citrullinates EP300/P300 at 'Arg-2142', which favors its interaction with NCOA2/GRIP1.
Especificaciones
| PADI4 | |
| Polyclonal | |
| Unconjugated | |
| Padi4 | |
| HL-60 PAD; PAD; PAD type IV; PAD4; Padi4; PADI5; PADI-H protein; PAD-R4; Pdi4; PDI5; peptidyl arginine deiminase 4; peptidyl arginine deiminase, type 4; peptidyl arginine deiminase, type IV; peptidyl arginine deiminase, type V; peptidylarginine deiminase IV; Peptidylarginine deiminase type alpha; protein-arginine deiminase type IV; Protein-arginine deiminase type-4 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 18602, 23569 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Frozen), Immunohistochemistry (Free Floating), Immunohistochemistry (Paraffin), Western Blot | |
| 2.85 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Q9UM07, Q9Z183 | |
| Padi4 | |
| Recombinant protein encompassing a sequence within the center region of human PAD4. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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