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Invitrogen™ PACS2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA567477
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Descripción
Immunogen sequence: TLDVFTERLPP SGRITKTESL VIPSTRSEGK QAGRRGRSTS LKERQAARPQ NERANSLDNE RCPDARSQLQ VQ Highest antigen sequence identity to the following orthologs - mouse 89%, rat 90%.
PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Especificaciones
| PACS2 | |
| Polyclonal | |
| Unconjugated | |
| PACS2 | |
| 6720425G15Rik; AW208651; AW489976; E230011J22; FLJ25488; Kiaa0602; mKIAA0602; Pacs1l; PACS1-like protein; Pacs2; PACS-2; Phosphofurin acidic cluster sorting protein 2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 23241 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry | |
| 0.5 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q86VP3 | |
| PACS2 | |
| Recombinant Human PACS2. Recombinant protein control fragment (Product #RP-108130). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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