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Invitrogen™ OLFM4 Monoclonal Antibody (02)
Descripción
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%). This antibody has specificity for Human OLFM4/GW112.
OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.
Especificaciones
Especificaciones
| Antígeno | OLFM4 |
| Aplicaciones | ELISA |
| Clasificación | Monoclonal |
| Clon | 02 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with no preservative |
| génica | OLFM4 |
| N.º de referencia del gen | Q6UX06 |
| Alias de gen | Antiapoptotic protein GW112; bA209J19.1; GC1; G-CSF-stimulated clone 1 protein; Gm296; Gm913; GW112; hGC-1; hOLfD; olfactomedin 4; olfactomedin-4; OlfD; OLFM4; OLM4; pPD4; PU.1 difference product 4; UNQ362; UNQ362/PRO698 |
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Título del producto
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