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Invitrogen™ NY-ESO-1 Monoclonal Antibody (E978)

Descripción
This antibody can react specifically with the 23 kDa NY-ESO-1 protein. During development reactivity was confirmed with human SKMEL-37 melanoma cells.
NY-ESO-1, a member of the CT (cancer/testis) family, is a tumor specific shared antigen with distinctive immunogenicity. The molecular basis of T cell-mediated antitumor immunity has been elucidated by the identification of a number of tumor antigens recognized by CD8+ T cells. Among these antigens, NY-ESO-1 is of particular interest because both the cytotoxic T lymphocyte and antibody have been shown to react with this antigen. The NY-ESO-1 has been detected in normal testis and in a range of human tumor types. NY-ESO-1 reactivity in testis is restricted germ cells, particularly in the spermatogonia.
Especificaciones
Especificaciones
| Antígeno | NY-ESO-1 |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Monoclonal |
| Clon | E978 |
| Concentración | 0.5 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 0.1% sodium azide; pH 7.4 |
| génica | CTAG1A |
| N.º de referencia del gen | P78358 |
| Alias de gen | Autoimmunogenic cancer/testis antigen NY-ESO-1; cancer/testis antigen 1; cancer/testis antigen 1A; cancer/testis antigen 1-A; cancer/testis antigen 6.1; CT6.1; CTAG; CTAG1; CTAG1A; CTAG1B; ESO1; l antigen family member 2; LAGE2; LAGE-2; LAGE2A; LAGE2B; New York Esophageal Squamous Cell Carcinoma 1; NY-ESO-1 |
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Título del producto
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