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NUMB Mouse anti-Human, Clone: OTI4C6, lyophilized, TrueMAB™
Descripción
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.
Especificaciones
Especificaciones
| Antígeno | NUMB |
| Aplicaciones | Western Blot |
| Clasificación | Monoclonal |
| Clon | OTI4C6 |
| Conjugado | Unconjugated |
| Formulación | PBS with 8% trehalose and no preservative; pH 7.3 |
| génica | NUMB |
| N.º de referencia del gen | P49757 |
| Alias de gen | C14orf41, S171, c14_5527 |
| Símbolos de los genes | NUMB |
| Show More |
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