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Invitrogen™ Noggin Monoclonal Antibody (A9)
Descripción
Noggin Monoclonal Antibody for Western Blot, IHC (P)
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.
Especificaciones
Especificaciones
| Antígeno | Noggin |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot, Western Blot |
| Clasificación | Monoclonal |
| Clon | A9 |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| génica | NOG |
| N.º de referencia del gen | P97466, Q13253, Q62809 |
| Alias de gen | NOG; Noggin; Noggin precursor; noggin; LOW QUALITY PROTEIN: noggin; SYM1; symphalangism 1 (proximal); SYNS1; SYNS1A |
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