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Invitrogen™ NOD4 Polyclonal Antibody
Descripción
Immunogen sequence: GLVRCFSTLQW LFRLDISFES QHILLRGDKT SRDMWATGSL PDFPAAAKFL GFRQRCIPRS LCLSECPLEP PSLTRLCATL KDCPGPLELQ LSCEFLSDQ Highest antigen sequence identity to the following orthologs - mouse 55%, rat 50%.
NOD4 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD4 contains a CARD-like domain, a central NOD domain and a large LRR region. NOD4, an IFN-gamma-inducible nuclear protein, plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. As a key negative regulator of NF-kappa-B and type I interferon signaling, NOD4 may be a useful target for manipulating immune responses against infectious or inflammation-associated diseases, including cancer.
Especificaciones
Especificaciones
| Antígeno | NOD4 |
| Aplicaciones | Immunocytochemistry |
| Clasificación | Polyclonal |
| Concentración | 0.05 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | NLRC5 |
| N.º de referencia del gen | Q86WI3 |
| Alias de gen | AI451557; AK220210; Caterpiller protein 16.1; CLR16.1; copine II; Cpne2; NLR family CARD domain containing 5; NLR family, CARD domain containing 5; Nlrc5; NOD27; NOD4; NOD-like receptor C5; Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5; nucleotide-binding oligomerization domains 27; protein NLRC5 |
| Símbolos de los genes | NLRC5 |
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Título del producto
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