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Invitrogen™ NIT1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA552317
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Descripción
Immunogen sequence: FLSLLCPGLR IPQLSVLCAQ PRPRAMAISS SSCELPLVAV CQVTSTPDKQ QNFKTCAELV REAARLGACL AFLPEAFDFI ARDPAETLHL SEPLGGKLLE EYTQLARECG LWLSLGGFHE RGQDWEQT Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 67%.
Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.
Especificaciones
| NIT1 | |
| Polyclonal | |
| Unconjugated | |
| NIT1 | |
| AI255805; Deaminated glutathione amidase; dGSH amidase; ESTM30; MGC57670; Nit1; nitrilase 1; nitrilase homolog 1; rCG_20134; W57327 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 4817 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q86X76 | |
| NIT1 | |
| Recombinant protein corresponding to Human NIT1. Recombinant protein control fragment (Product #RP-89178). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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