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NCAM-1 (CD56) Mouse anti-Human, Brilliant Violet 421, Clone: R19-760, BD Optibuild™

Código de producto. 15838859
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Cantidad:
50 μg
Tamaño de la unidad:
cada uno
Código de producto. Cantidad unitSize
15838859 50 μg cada uno
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Código de producto. 15838859

Marca: BD Biosciences 744217

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Descripción

Mouse Monoclonal Antibody

The R19-760 monoclonal antibody specifically binds to NCAM-1 (Neural cell adhesion molecule 1) that is also known as CD56 and NKH1. NCAM-1 is a heavily glycosylated transmembrane protein and a member of the Ig supergene family. NCAM-1 represents an isoform of the neural cell adhesion molecule (NCAM). In the hematopoietic system, it is present on approximately 10% to 25% of peripheral blood lymphocytes. It is expressed on natural killer (NK) cells and a subset of T cells, NKT cells. It is not expressed on myeloid cells, erythrocytes or B cells. This molecule appears to function as an adhesion molecule and can serve as a panspecific NK-cell marker. The R19-760 antibody recognizes an epitope in the NCAM-1 (CD56) extracellular domain that resists destruction due to cellular fixation with BD Phosflow™ Lyse/Fix Buffer and permeabilization with BD Phosflow™ Perm Buffer III.

The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407nm and Em Max at 421nm, BD Horizon BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter set (eg, 450/50nm filter). BD Horizon BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to Pacific Blue conjugates. BV421 is a polymer-based dye excited by the violet laser and is one of the brightest fluorochromes offered by BD Biosciences. Conjugates are typically 10 times brighter than Pacific Blue™ conjugates and are often as bright as or brighter than PE conjugates. Due to nearly identical excitation and emission properties but different spillover characteristics, BD Horizon BV421, Pacific Blue™, and BD Horizon™ V450 cannot be used simultaneously.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno NCAM-1 (CD56)
Clasificación Monoclonal
Clon R19-760
Concentración 0.2mg/mL
Conjugado Brilliant Violet 421
Formulación Aqueous buffered solution containing ≤0.09% sodium azide.
Alias de gen N-CAM-1, Neural cell adhesion molecule 1, NKH1, MSK39, Leu-19
Especie del huésped Mouse
Inmunógeno Human NCAM1 Recombinant Protein
Método de purificación Affinity Purified
Cantidad 50 μg
Estado normativo RUO
Primario o secundario Primary
Especies diana Human
Contenido y almacenamiento Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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