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Descripción
The antibody can recognize all the 8 isoforms of MYOF.
Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
Especificaciones
Especificaciones
| Antígeno | Myoferlin |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Flow Cytometry, Immunofluorescence |
| Clasificación | Polyclonal |
| Concentración | 0.26 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| génica | MYOF |
| N.º de referencia del gen | Q9NZM1 |
| Alias de gen | Fer 1 like protein 3, FER1L3, KIAA1207, MYOF, Myoferlin |
| Símbolos de los genes | MYOF |
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Título del producto
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