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Invitrogen™ MYCT1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA524018
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Descripción
MYCT1 Polyclonal Antibody for Western Blot, Flow
MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
Especificaciones
| MYCT1 | |
| Polyclonal | |
| Unconjugated | |
| Myct1 | |
| 1110020B04Rik; AI225941; AI642973; MTLC; MTMC1; MT-MC1; myc target 1; myc target in myeloid cells 1; myc target in myeloid cells protein 1; Myc target protein 1; Myct1 | |
| Rabbit | |
| Antigen Affinity Chromatography, Protein A | |
| RUO | |
| 80177 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Flow Cytometry, Western Blot | |
| 0.5 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| Q8N699 | |
| Myct1 | |
| KLH conjugated synthetic peptide between 135-163 amino acids from the C-terminal region of human MYCT1. | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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