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Invitrogen™ MYCT1 Polyclonal Antibody

Descripción
MYCT1 Polyclonal Antibody for Western Blot, Flow
MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
Especificaciones
Especificaciones
| Antígeno | MYCT1 |
| Aplicaciones | Flow Cytometry, Western Blot |
| Clasificación | Polyclonal |
| Concentración | 0.5 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 0.09% sodium azide; pH 7.4 |
| génica | Myct1 |
| N.º de referencia del gen | Q8N699 |
| Alias de gen | 1110020B04Rik; AI225941; AI642973; MTLC; MTMC1; MT-MC1; myc target 1; myc target in myeloid cells 1; myc target in myeloid cells protein 1; Myc target protein 1; Myct1 |
| Símbolos de los genes | Myct1 |
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Título del producto
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