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Invitrogen™ Munc13-4 Polyclonal Antibody

Descripción
Recommended positive controls: A431, mouse lung. Predicted reactivity: Mouse (87%), Rat (91%), Bovine (86%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Especificaciones
Especificaciones
| Antígeno | Munc13-4 |
| Aplicaciones | Western Blot |
| Clasificación | Polyclonal |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| génica | Unc13d |
| N.º de referencia del gen | B2RUP2, Q70J99 |
| Alias de gen | 2610108D09Rik; FHL3; HLH3; HPLH3; Jinx; likely ortholog of H. sapiens unc-13 homolog D (UNC13D); mFLJ00067; munc 13-4; Munc13-4; Protein unc-13 homolog D; unc-13 homolog D; unc-13 homolog D (C. elegans); Unc13d |
| Símbolos de los genes | Unc13d |
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Título del producto
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