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Invitrogen™ Munc13-4 Polyclonal Antibody
Goat Polyclonal Antibody
Marca: Invitrogen™ PA518550
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Descripción
This antibody is predicted to react with bovine, canine, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Especificaciones
| Munc13-4 | |
| Polyclonal | |
| Unconjugated | |
| Unc13d | |
| 2610108D09Rik; FHL3; HLH3; HPLH3; Jinx; likely ortholog of H. sapiens unc-13 homolog D (UNC13D); mFLJ00067; munc 13-4; Munc13-4; Protein unc-13 homolog D; unc-13 homolog D; unc-13 homolog D (C. elegans); Unc13d | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 201294, 70450 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| B2RUP2, Q70J99 | |
| Unc13d | |
| Synthetic peptide sequence (ETQKHKKDLHPLFD) corresponding to the internal amino acids of UNC13D (aa 967-980). | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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