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Invitrogen™ Munc13-4 Polyclonal Antibody
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Código de producto. 13455387
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Código de producto. Cantidad unitSize
13455387 100 μL 100 microlitros
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Código de producto. 13455387

Marca: Invitrogen™ PA530883

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Descripción

Rabbit Polyclonal Antibody

Recommended positive controls: A431, mouse lung. Predicted reactivity: Mouse (87%), Rat (91%), Bovine (86%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno Munc13-4
Aplicaciones Western Blot
Clasificación Polyclonal
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
génica Unc13d
N.º de referencia del gen B2RUP2, Q70J99
Alias de gen 2610108D09Rik; FHL3; HLH3; HPLH3; Jinx; likely ortholog of H. sapiens unc-13 homolog D (UNC13D); mFLJ00067; munc 13-4; Munc13-4; Protein unc-13 homolog D; unc-13 homolog D; unc-13 homolog D (C. elegans); Unc13d
Símbolos de los genes Unc13d
Especie del huésped Rabbit
Inmunógeno Recombinant protein encompassing a sequence within the N-terminus region of human Munc 13-4. The exact sequence is proprietary.
Método de purificación Antigen affinity chromatography
Cantidad 100 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 201294, 70450
Especies diana Human, Mouse
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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