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Invitrogen™ MRP3 Monoclonal Antibody (M3II-21)
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Código de producto. 11574982
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Cantidad:
1 mL
Tamaño de la unidad:
1 ml
Código de producto. Cantidad unitSize
11574982 1 mL 1 ml
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Código de producto. 11574982

Marca: Invitrogen™ MA135679

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Descripción

Mouse Monoclonal Antibody

The antibody reacts with an internal epitope of MRP3, a 190-200 kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. M3II-21 was raised against a bacterial fusion protein of MRP3, containing amino acids 830-949 of the protein. M3II-21 does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products. M3II-21 has potential value for detection of MRP3-mediated drug-resistance in human tumor samples.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno MRP3
Aplicaciones Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
Clasificación Monoclonal
Clon M3II-21
Concentración Conc. Not Determined
Conjugado Unconjugated
Formulación Tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
génica ABCC3
N.º de referencia del gen O15438
Alias de gen ABC31; ABCC3; ATP binding cassette subfamily C member 3; ATP-binding cassette sub-family C member 3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; canalicular multispecific organic anion transporter 2; canicular multispecific organic anion transporter; cMOAT2; DKFZp686E22157; EST90757; MLP2; MLP-2; MOAT-D; Mrp3; MRP-like protein 2; multidrug resistance associated protein; multidrug resistance protein 3; multidrug resistance-associated protein 3; multi-specific organic anion transporter D; organic anion transporter
Símbolos de los genes ABCC3
Especie del huésped Mouse
Inmunógeno MRP3 aa 830-949.
Cantidad 1 mL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 8714
Especies diana Human
Contenido y almacenamiento 2°C to 8°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG2b
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