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Invitrogen™ MRGPRX2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA533951
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Descripción
Percent identity with other species by BLAST analysis: Human, Orangutan, Monkey (100%) Chimpanzee, Gorilla, Gibbon, Marmoset (86%).
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled. Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion.
Especificaciones
| MRGPRX2 | |
| Polyclonal | |
| Unconjugated | |
| MRGPRX2 | |
| G protein-coupled receptor MRGX2; G370024M05Rik; MAS related GPR family member X2; Mas-related G protein-coupled receptor G3; MAS-related GPR, member B10; MAS-related GPR, member X2; mas-related G-protein coupled receptor member B10; Mas-related G-protein coupled receptor member X2; MGRG3; MrgB10; Mrgprb10; Mrgprx2; MRGX2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 117194 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 1 mg/mL | |
| PBS with 0.1% sodium azide | |
| Q96LB1 | |
| MRGPRX2 | |
| Synthetic 14 amino acid peptide from 2nd extracellular domain of human MRGPRX2 / MRGX2. | |
| 50 μg | |
| Primary | |
| Human, Monkey | |
| Antibody | |
| IgG |
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