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Invitrogen™ MRCK gamma Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA5100763
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Descripción
Antibody detects endogenous levels of total MRCKG.
CDC42 BPG serine/threonine kinase is encoded by the CDC42BPG gene. It acts as a downstream effector of CDC42 in cytoskeletal reorganization, and contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and MLC2 phosphorylation. It belongs to the AGC protein kinase family, DMPK subfamily. It contains an N-terminal kinase domain, followed by a coiled-coil domain, a second coiled-coil domain containing a kinase inhibitory motif (KIM), a variable region, a cysteine-rich domain, a pleckstrin (PLEK; 173570) homology (PH) domain, a citron (605629) homology (CNH) domain, and a C-terminal CDC42 (116952)/RAC (602048) interactive binding (CRIB) domain.
Especificaciones
| MRCK gamma | |
| Polyclonal | |
| Unconjugated | |
| CDC42BPG | |
| BC046418; CDC42 binding protein kinase gamma; CDC42 binding protein kinase gamma (DMPK-like); CDC42-binding protein kinase gamma; CDC42BPG; DMPK2; DMPK-like gamma; HSMDPKIN; KAPPA-200; MRCK gamma; MRCKG; MRCKgamma; Myotonic dystrophy kinase-related CDC42-binding kinase gamma; myotonic dystrophy protein kinase like protein; myotonic dystrophy protein kinase-like alpha; myotonic dystrophy protein kinase-like gamma; serine/threonine-protein kinase MRCK gamma | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 240505, 55561 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q6DT37, Q80UW5 | |
| CDC42BPG | |
| A synthesized peptide derived from human CDC42BPG(Accession Q6DT37), corresponding to amino acid residues L1393-F1443. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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