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fMLP Receptor Mouse anti-Human, Alexa Fluor 647, Clone: 5F1, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 565623
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Descripción
The 5F1 monoclonal antibody specifically binds to the N-formyl-leucyl-phenylalanine receptor (fMLP receptor), which is also known as, Formyl peptide receptor 1 (FPR1). This 55-70 kDa receptor is expressed on neutrophils, monocytes, macrophages, and liver parenchymal cells. It is composed of seven hydrophobic membrane spanning regions and is a member of the rhodopsin superfamily of G protein-coupled receptors. N-formyl peptides interact with fMLP receptors and induce neutrophil chemotaxis, phagocytosis, production of superoxide radicals and release of proteolytic enzymes. The binding of the 5F1 antibody to the fMLP receptor can be blocked by fMLP peptide.
Especificaciones
| fMLP Receptor | |
| Monoclonal | |
| Alexa Fluor 647 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human fMLP receptor Transfected Cell Line | |
| 100 Tests | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| Flow Cytometry | |
| 5F1 | |
| fMet-Leu-Phe receptor; formyl peptide receptor 1; FPR1; FPR | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Human | |
| IgG1 κ |
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