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HPB-ALL, Mouse, Clone: MEM-258, Abnova™
Mouse monoclonal antibody raised against native CD46.
Marca: Abnova MAB0930.100ug
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Descripción
The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene. [provided by RefSeq
Especificaciones
| HPB-ALL | |
| Monoclonal | |
| 1 mg/mL | |
| Mouse monoclonal antibody raised against native CD46. | |
| In TBS, pH 8.0 (0.09% sodium azide) | |
| MCP/MGC26544/MIC10/TLX/TRA2.10 | |
| Mouse | |
| 100 μg | |
| Primary | |
| This antibody recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein). | |
| Store at 4°C. Do not freeze. | |
| IgG1 |
| Flow Cytometry, Immunoprecipitation, Western Blot | |
| MEM-258 | |
| Unconjugated | |
| The optimal working dilution should be determined by the end user. | |
| CD46 | |
| CD46 | |
| Native purified CD46 from human T cell line HPB-ALL. | |
| RUO | |
| 4179 | |
| Bovine, Human | |
| Liquid |
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