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Invitrogen™ MMP13 Monoclonal Antibody (VIIIA2)
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Código de producto. 11365013
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Cantidad:
500 μL
Tamaño de la unidad:
500 microlitros
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11365013 500 μL 500 microlitros
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Código de producto. 11365013 Proveedor Invitrogen™ N.º de proveedor MA514238

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Descripción

Mouse Monoclonal Antibody

MA5-14238 targets MMP-13 (Collagenase-3) in IHC (P) and IP applications and shows reactivity with Human, mouse, and Rabbit samples. The MA5-14238 immunogen is human recombinant collagenase-3 protein.

MMP13 (collagense 3) plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC, and ACAN. MMP13 cleaves tripal helical collagens, including type I, II, and III collagen - but has the highest activity with soluble type II collagen. It can degrade collagen type IV, XIV, and X. MMP13 plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization, and ossification. It is required for normal embryonic bone development and ossificaiton. Mutations affecting the gene can lead to spondyloepimetaphyseal dysplasia Missouri type, metaphyseal anadysplasia 1, and metaphyseal dysplasia Sphar type.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno MMP13
Aplicaciones Western Blot, Immunoprecipitation, Western Blot
Clasificación Monoclonal
Clon VIIIA2
Concentración 0.2 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
génica MMP13
N.º de referencia del gen P33435, P45452
Alias de gen cb1034; Clg; CLG3; Collagenase; collagenase 3; collagenase 3a; matrix metalloproteinase 13a; collagenase-1; Collagenase3; Collagenase-3; collagenase-3 precursor; interstitial collagenase; MANDP1; matrix metallo protease; matrix metallopeptidase 13; matrix metallopeptidase 13 (collagenase 3); matrix metallopeptidase 13a; matrix metallopeptidase 13a (collagenase 3); matrix metalloproteinase 13; matrix metalloproteinase 13 (collagenase 3); matrix metalloproteinase-13; matrix metalloproteinase-13; MMP-13; interstitial protein; MMP; Mmp1; MMP13; MMP-13; mmp13 protein; mmp13a; MMPLg; MMPLh; MMPs; Procollagenase 3; UMRCASE; ZFMMP13
Símbolos de los genes MMP13
Especie del huésped Mouse
Inmunógeno Human recombinant collagenase-3 protein.
Método de purificación Protein G
Cantidad 500 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 17386, 4322
Especies diana Human, Mouse
Contenido y almacenamiento 4°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1 κ
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