missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Anticuerpos
  4. Anticuerpos primarios
  5. Todos los anticuerpos primarios
  6. 11519342

Invitrogen™ MLH1 Monoclonal Antibody (G168-15)
GREENER_CHOICE

Código de producto. 11519342
Change view
Click to view available options
Cantidad:
500 μL
Tamaño de la unidad:
500 microlitros
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Código de producto. Cantidad unitSize
11519342 500 μL 500 microlitros
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Este artículo no se puede devolver. Vea la política de devoluciones
Código de producto. 11519342 Proveedor Invitrogen™ N.º de proveedor MA125669

Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.

This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Suggested positive controls for this product are tonsil and colon carcinoma.

MLH1 is a DNA mismatch repair protein. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related to human carcinogenesis. The importance of mismatch repair genes became apparent with the identification of the genetic basis for hereditary nonpolyposis colon cancer (HNPC). MSHS2 is involved in the initial cognition of mismatch nucleotides during the replication mismatch repair process. It is thought that after MSH2 binds to a mismatched DNA duplex it is joined by a heterodimer of MLH1 and PMSH, which together help facilitate the later steps in mismatch repair.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno MLH1
Aplicaciones Immunohistochemistry (Paraffin)
Clasificación Monoclonal
Clon G168-15
Concentración Conc. Not Determined
Conjugado Unconjugated
Formulación Tissue culture supernatant with 0.09% sodium azide
génica Mlh1
N.º de referencia del gen P40692
Alias de gen 1110035C23Rik; AI317206; AI325952; AI561766; COCA2; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; DNA mismatch repair protein Mlh1-like protein; FCC2; hMLH1; HNPCC; HNPCC2; I79_014127; MGC5172; mismatch repair protein 1; MLH1; MLH-1; mutL homolog 1; mutL homolog 1 (E. coli); mutL homolog 1, colon cancer, nonpolyposis type 2; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); mutL protein homolog 1
Símbolos de los genes Mlh1
Especie del huésped Mouse
Inmunógeno Full length recombinant MLH.
Método de purificación Protein A
Cantidad 500 μL
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 4292
Especies diana Human
Contenido y almacenamiento 4°C
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.