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Invitrogen™ MICAL2 Polyclonal Antibody

Descripción
Antibody detects endogenous levels of total MICAL2.
MICALs (Molecules Interacting with CasL) are atypical multidomain flavoenzymes with diverse cellular functions. There are three known isoforms, MICAL1, MICAL2 and MICAL3, as well as the MICAL-like proteins MICAL-L1 and MICAL-L2. MICAL2 has three conserved domains: an N-terminal flavin adenine dinucleotide (FAD) binding domain, a calponin homology (CH) domain and a Lin11, Isl-1 and Mec-3 (LIM) domain. It has been demonstrated that MICAL2 could regulate actin stress fibers and is required for normal actin organization. In addition, MICAL2-PV, a novel splicing variants of MICAL2, has been reported to be involved in cancer progression of prostate cancer.
Especificaciones
Especificaciones
| Antígeno | MICAL2 |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Polyclonal |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| génica | Mical2 |
| N.º de referencia del gen | D4A1F2, O94851, Q8BML1 |
| Alias de gen | [F-actin]-monooxygenase MICAL2; 5330438E18Rik; 9530064J02; flavoprotein oxidoreductase MICAL2; Kiaa0750; Mical2; MICAL-2; MICAL2PV1; MICAL2PV2; microtubule associated monooxygenase, calponin and LIM domain containing 2; microtubule associated monoxygenase, calponin and LIM domain containing 2; mKIAA0750; mMical2; molecule interacting with CasL protein 2; protein MICAL-2; protein-methionine sulfoxide oxidase MICAL2; RGD1311773 |
| Símbolos de los genes | Mical2 |
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