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Invitrogen™ mGluR5 Polyclonal Antibody
Sheep Polyclonal Antibody
Marca: Invitrogen™ PA547630
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Descripción
In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant human (rh) mGluR1 is observed and less than 5% cross-reactivity with rhmGluR2 and rhmGluR3 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
Especificaciones
| mGluR5 | |
| Polyclonal | |
| Unconjugated | |
| Grm5 | |
| 6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86 | |
| Sheep | |
| Antigen affinity chromatography | |
| RUO | |
| 2915 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Immunohistochemistry, Western Blot | |
| 0.2 mg/mL | |
| PBS with 5% trehalose and No Preservative | |
| P41594 | |
| Grm5 | |
| Mouse myeloma cell line NS0-derived recombinant human mGluR5 Gln21-Ser509. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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