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Invitrogen™ MEIOB Polyclonal Antibody

Descripción
Immunogen sequence: NMANLKVIGI VIGKTDVKGF PDRKNIGSER YTFSFTIRDS PAHFVNAASW GNEDYIKSLS DSFRVGDCVI IENPLIQRKE I Highest antigen sequence indentity to the following orthologs: Mouse - 86%, Rat - 88%.
Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
Especificaciones
Especificaciones
| Antígeno | MEIOB |
| Aplicaciones | Immunocytochemistry, Immunofluorescence |
| Clasificación | Polyclonal |
| Concentración | 0.1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| génica | MEIOB |
| N.º de referencia del gen | Q8N635 |
| Alias de gen | 4930528F23Rik; C16orf73; C6H16orf73; gs129; Meiob; meiosis specific with OB domains; meiosis specific with OB-fold; meiosis-specific with OB domain-containing protein; MLZ-675; Protein expressed in male leptotene and zygotene spermatocytes 675 |
| Símbolos de los genes | MEIOB |
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Título del producto
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