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Invitrogen™ MCP-2 Polyclonal Antibody

Descripción
In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) MCP-2 is observed, and less then 1% cross-reactivity with rhMCP-4, recombinant mouse (rm) MCP-5, and rmEotaxin is observed. Reconstitute at 0.2 mg/mL in sterile PBS.
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
Especificaciones
Especificaciones
| Antígeno | MCP-2 |
| Aplicaciones | Western Blot |
| Clasificación | Polyclonal |
| Concentración | 0.2 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 5% trehalose and No Preservative |
| génica | CCL8 |
| N.º de referencia del gen | Q9Z121 |
| Alias de gen | 1810063B20Rik; AB023418; C-C motif chemokine 8; C-C motif chemokine ligand 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; MCP-2(6-76); monocyte chemoattractant protein 2; monocyte chemoattractant protein-2; monocyte chemotactic protein 2; SCYA10; SCYA8; small inducible cytokine A8; small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2); small-inducible cytokine A8 |
| Símbolos de los genes | CCL8 |
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Título del producto
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