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Invitrogen™ MCP-1 Monoclonal Antibody (2D8)
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Código de producto. 15342290
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Cantidad:
100 μg
Tamaño de la unidad:
100 microgramos
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15342290 100 μg 100 microgramos
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Product Code. 15342290 Supplier Invitrogen™ Supplier No. MA517040

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Description

Mouse Monoclonal Antibody

MA5-17040 targets CCL2 in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human, Mouse, and Non-human primate samples. The MA5-17040 immunogen is purified recombinant fragment of human CCL2 expressed in E. Coli. MA5-17040 detects CCL2 which has a predicted molecular weight of approximately 11kDa.

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
TRUSTED_SUSTAINABILITY

Specifications

Antígeno MCP-1
Aplicaciones ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Clasificación Monoclonal
Clon 2D8
Concentración 1 mg/mL
Conjugado Unconjugated
Formulación PBS with 0.05% sodium azide
génica Ccl2
N.º de referencia del gen P10148, P13500
Alias de gen Acidic seminal fluid protein; AI323594; C-C motif chemokine 2; C-C motif chemokine ligand 2; Ccl2; chemokine (C-C motif) ligand 2; GDCF-2; HC11; H-MCP-1; HSMCR30; immediate-early serum-responsive JE protein; immediate-early serum-responsive protein JE; Je; MCAF; Mcp1; MCP-1; MCP1A; MCP-1A; MGC9434; Monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; monocyte chemotactic protein 1A; Monocyte secretory protein JE; monocyte-chemoattractant protein-1 precursor; platelet-derived growth factor-inducible protein JE; RP23-350G1.3; SCYA2; Sigje; small inducible cytokine A2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je); small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible gene JE; small-inducible cytokine A2; SMC-CF
Símbolos de los genes Ccl2
Especie del huésped Mouse
Inmunógeno Purified recombinant fragment of human CCL2 expressed in E. Coli.
Método de purificación Protein G
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 20296, 6347
Especies diana Human, Mouse, Monkey
Contenido y almacenamiento Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Tipo de producto Antibody
Formulario Liquid
Isotype IgG1
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