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Invitrogen™ MASP1 Monoclonal Antibody (38:12-3)
Rat Monoclonal Antibody
Marca: Invitrogen™ MA533365
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Descripción
Product is supplied at 1 mL (100 μL/mL). Application Notes: This product can be used as a detector in immunoassays.
MBL is a key component in immune response in that it can directly trigger neutralization of invading microorganisms by an Ab-independent mechanism. Mutations of human MBL are associated with immunodeficiency resulting from a reduction in the ability of the mutant MBL to initiate complement fixation. In human, three types of MBL-associated serine proteases, MASP-1, MASP-2 and MASP-3, and a truncated form of MASP-2 (small MBL-associated protein; sMAP or MAp19) complex with MBL to activate the lectin pathway of the complement system. MASP-3 is an alternatively spliced product from the MASP-1 gene. The heavy/A chains are identical between MASP-1 and MASP-3 but the light/B chains are entirely different. Activated MASPs subsequently cleave and activate downstream components of the complement pathway.
Especificaciones
| MASP1 | |
| Monoclonal | |
| 100 μg/mL | |
| PBS with 0.1% BSA and 0.02% sodium azide | |
| P48740 | |
| MASP1 | |
| Protein G | |
| RUO | |
| 5648 | |
| 4°C | |
| Liquid |
| ELISA, Western Blot | |
| 38:12-3 | |
| Unconjugated | |
| MASP1 | |
| 3MC1; AW048060; C4/C2 activating component of Ra-reactive factor; CCPII; Complement factor MASP-3; complement-activating component of Ra-reactive factor; Crarf; CRARF1; mannan binding lectin serine peptidase 1; mannan-binding; mannan-binding lectin serine peptidase 1; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor); mannan-binding lectin serine protease 1; Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain; Mannose-binding lectin-associated serine protease 1; mannose-binding protein associated serine protease-1; mannose-binding protein-associated serine protease; MAP1; MAp44; MASP; MASP1; MASP-1; Masp1/3; MASP3; PRSS5; Ra-reactive factor serine protease p100; raRF; Serine protease 5; serine protease MASP1 | |
| Rat | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
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