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Invitrogen™ MARCH1 Polyclonal Antibody

Description
MARCH1 Polyclonal Antibody for Western Blot, IHC (P)
E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell surface localization thus sequestering them in the intracellular endosomal system.
Specifications
Specifications
| Antígeno | MARCH1 |
| Aplicaciones | Immunohistochemistry (Paraffin), Western Blot |
| Clasificación | Polyclonal |
| Concentración | 1 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| génica | MARCH1 |
| N.º de referencia del gen | Q8TCQ1 |
| Alias de gen | 1-Mar; 2900024D24Rik; BB085186; E3 ubiquitin-protein ligase MARCH1; MARCH1; MARCHF1; MARCH-I; membrane associated ring finger 1; membrane associated ring-CH-type finger 1; membrane-associated ring finger (C3HC4) 1; membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase; membrane-associated RING finger protein 1; Membrane-associated RING-CH protein I; RGD1305148; RING finger protein 171; RING-type E3 ubiquitin transferase MARCH1; RNF171 |
| Símbolos de los genes | MARCH1 |
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