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Invitrogen™ MAPK15 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA514488
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Descripción
MAPK15 Polyclonal Antibody for Western Blot, IHC (P)
The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.
Especificaciones
| MAPK15 | |
| Polyclonal | |
| PBS with 0.09% sodium azide; pH 7.4 | |
| Q8TD08 | |
| MAPK15 | |
| KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human MAPK15. | |
| 400 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Immunohistochemistry (Paraffin), Western Blot | |
| Unconjugated | |
| MAPK15 | |
| BC048082; EC 2.7.11.24; ERK7; ERK-7; ERK8; ERK-8; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15; Mapk15; Mitogen-activated protein kinase 15 | |
| Rabbit | |
| Ammonium sulfate precipitation, Size-exclusion - Dialysis | |
| RUO | |
| 225689 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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