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MAGE 1 Antibody (MA454), Novus Biologicals™
Mouse Monoclonal Antibody has been used in 1 publication
Marca: Novus Biologicals NBP2-29469-20ug
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Descripción
MAGE 1 Monoclonal specifically detects MAGE 1 in Human, Rat, Canine samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA.
Especificaciones
| MAGE 1 | |
| Monoclonal | |
| 0.2 mg/ml | |
| Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunohistochemistry 0.5-1ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, Sandwich ELISA | |
| Antigen MZ2-E, Cancer/testis antigen 1.1, cancer/testis antigen family 1, member 1, CT1.1melanoma antigen family A 1, MAGE-1 antigen, MAGE1A, MAGE1melanoma antigen MAGE-1, melanoma antigen family A, 1 (directs expression of antigen MZ2-E), melanoma-associated antigen 1, melanoma-associated antigen MZ2-E, MGC9326 | |
| Mouse | |
| 44 kDa | |
| 20 ug | |
| Apoptosis, Cancer, Melanoma Cell Markers, Tumor Suppressors | |
| 4100 | |
| Human, Rat, Canine | |
| Purified |
| Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen) | |
| MA454 | |
| Unconjugated | |
| P43355 | |
| MAGEA1 | |
| Recombinant full-length human MAGE 1 protein (Uniprot: P43355) | |
| Protein A or G purified | |
| RUO | |
| Primary | |
| Recognizes a protein of 42-46kDa, identified as MAGE-1. This monoclonal antibody does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy. | |
| Store at 4C. | |
| IgG1 κ |
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For Research Use Only
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