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Invitrogen™ LIF Polyclonal Antibody

Código de producto. 17807142
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Cantidad:
100 μg
Tamaño de la unidad:
100 microlitros
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17807142 100 μg 100 microlitros
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Código de producto. 17807142 Proveedor Invitrogen™ N.º de proveedor PA5142991

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Descripción

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Leukemia inhibitory factor (LIF) is a 20 kDa protein that belongs to the IL-6 receptor family. It binds to a heterodimeric membrane receptor made up of a LIF-specific subunit, gp190 or LIFR, and the subunit gp130, which is shared with the other members of the IL-6 family. LIF expression has been observed in various tissues including thymus, lung, and neuronal tissue. LIF can be up-regulated by pro-inflammatory cytokines such as TNFα and IL-17, and elevated levels of LIF have been found in cases of rheumatoid arthritis, neural injury, systemic inflammation, and tuberculosis. LIF displays diverse biological effects, but is best known for its ability to inhibit the differentiation of embryonic stem cells in mice and contribute to stem cell self-renewal.Human and mouse LIF share 79% sequence homology and exhibit cross-species activity. However, LIF inhibition of stem cell differentiation appears to be mouse-specific.
TRUSTED_SUSTAINABILITY

Especificaciones

Antígeno LIF
Aplicaciones Flow Cytometry, Immunohistochemistry (Paraffin)
Clasificación Polyclonal
Concentración 0.5 mg/mL
Conjugado Unconjugated
Formulación TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
génica Lif
N.º de referencia del gen P15018
Alias de gen CDF; cholinergic differentiation factor; cholinergic neuronal differentiation factor; d factor; DIA; differentiation inhibitory activity; differentiation-inducing factor; differentiation-stimulating factor; Emfilermin; hepatocyte-stimulating factor III; HILDA; human interleukin in DA cells; leukemia inhibitory factor; leukemia inhibitory factor (cholinergic differentiation factor); LIF; Melanoma-derived LPL inhibitor; MLPLI; myeloid leukaemia inhibitory factor
Símbolos de los genes Lif
Especie del huésped Goat
Inmunógeno Peptide with sequence RLCSKYHVGHVDVT (aa 154-167).
Método de purificación Ammonium sulfate precipitation
Cantidad 100 μg
Estado normativo RUO
Primario o secundario Primary
ID de gen (Entrez) 3976
Especies diana Human
Contenido y almacenamiento -20°C, Avoid Freeze/Thaw Cycles
Tipo de producto Antibody
Formulario Liquid
Isotype IgG
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