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Invitrogen™ LGI1 Recombinant Rabbit Monoclonal Antibody (23GB5930), Invitrogen™

Descripción
The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.
Especificaciones
Especificaciones
| Antígeno | LGI1 |
| Aplicaciones | Flow Cytometry, Western Blot, Immunocytochemistry |
| Clasificación | Recombinant Monoclonal |
| Clon | 23GB5930 |
| Concentración | 0.6 mg/mL |
| Conjugado | Unconjugated |
| Formulación | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| génica | LGI1 |
| N.º de referencia del gen | O95970 |
| Alias de gen | ADLTE; ADPAEF; ADPEAF; BB130740; EPITEMPIN; Epitempin 1; Epitempin-1; EPT; ETL1; IB1099; leucine rich glioma inactivated 1; leucine-rich glioma inactivated 1; leucine-rich glioma-inactivated protein 1; leucine-rich repeat LGI family, member 1; leucine-rich, glioma inactivated 1; LGI1; OTTHUMP00000020121; OTTHUMP00000020122; UNQ775/PRO1569 |
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Título del producto
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